Drugs / JS007
last change 3 days ago re-read 9 days ago

JS007

Monoclonal antibody targets CTLA4 via inhibition

Developed for
hepatocellular carcinoma · malignant pancreatic neoplasm
Investigated by
Shanghai Junshi Bioscience Co., Ltd. · Fudan University

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05049265 Nov 2021 → Sep 2022 — Shanghai Junshi Bioscience Co., Ltd. Unknown No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06370754 Apr 2024 → Apr 2026 overdue malignant pancreatic neoplasm Fudan University Not yet recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT06954467 May 2025 → Dec 2027 expected hepatocellular carcinoma Shanghai Junshi Bioscience Co., Ltd. Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07823348 Oct 2026 → Oct 2029 expected hepatocellular carcinoma Shanghai Junshi Bioscience Co., Ltd. Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as JS007 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06954467 ↗
3

NCT06370754 ↗

NCT05049265 ↗

NCT07823348 ↗

Action Inhibit “Blocking cytotoxic T lymphocyte-associated antigen-4 (CTLA-4)” PMID 39354625 ↗ Oct 2024
Modality Monoclonal antibody “CTLA-4 monoclonal antibody” NCT07823348 ↗
Route Intravenous “JS007 was administered intravenously every 3 weeks at doses of 0.03, 0.3, 1, 3, and 10 mg/kg” PMID 39354625 ↗ Oct 2024
Target CTLA4 “Blocking cytotoxic T lymphocyte-associated antigen-4 (CTLA-4)” PMID 39354625 ↗ Oct 2024