Drugs / Rocbrutinib

Trials 14 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 18 trials
Phase 1 NCT07570017 May 2026 → Dec 2027 expected diffuse large B-cell lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Not yet recruiting No outcome recorded
Phase 1 NCT07374224 Mar → Jun 2026 overdue Guangzhou Lupeng Pharmaceutical Company LTD. Recruiting No outcome recorded
Phase 1 NCT06251180 Apr 2024 → Dec 2025 overdue B-cell non-Hodgkin lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Recruiting No outcome recorded
Phase 1 NCT06126861 Dec 2023 → Feb 2024 Guangzhou Lupeng Pharmaceutical Company LTD. Completed No outcome recorded
Phase 1 NCT05917964 Jun → Aug 2023 mantle cell lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Completed No outcome recorded
Phase 1 NCT05432713 May → Nov 2022 multiple sclerosis, neuromyelitis optica Guangzhou Lupeng Pharmaceutical Company LTD. Completed No outcome recorded
Phase 1 NCT04775745 Jul 2021 → Dec 2027 expected Waldenstrom macroglobulinemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, diffuse large B-cell lymphoma, follicular lymphoma +3 Newave Pharmaceutical Inc Recruiting No outcome recorded
Phase 1 NCT04993690 Jul 2021 → Dec 2026 expected B-cell non-Hodgkin lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07609862 May 2026 → Jun 2029 expected Waldenstrom macroglobulinemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, diffuse large B-cell lymphoma, follicular lymphoma +1 Guangzhou Lupeng Pharmaceutical Company LTD. Not yet recruiting No outcome recorded
Phase 23 trials
Phase 2 NCT07189065 Nov 2025 → Dec 2027 expected diffuse large B-cell lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Recruiting No outcome recorded
Phase 2 NCT06978088 Jun 2025 → Jun 2029 expected chronic lymphocytic leukemia/small lymphocytic lymphoma Zulfa Omer Recruiting No outcome recorded
Phase 2 NCT05716087 Feb 2023 → Dec 2024 overdue mantle cell lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Active not recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT07342478 Apr 2026 → Oct 2029 expected chronic lymphocytic leukemia/small lymphocytic lymphoma Newave Pharmaceutical Inc Recruiting No outcome recorded
Phase 3 NCT07377578 Feb 2026 → May 2031 expected mantle cell lymphoma Guangzhou Lupeng Pharmaceutical Company LTD. Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as Rocbrutinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT05716087
7

NCT07342478

NCT07377578

NCT07609862

NCT07189065

NCT07570017

NCT06251180

NCT07374224

Known as LP-168 “Rocbrutinib (LP-168) is a novel, highly selective, fourth-generation Bruton's tyrosine kinase (BTK) inhibitor” NCT07377578
7

“Rocbrutinib (LP-168) is a selective next-generation inhibitor of BTK” NCT07342478

NCT04775745

NCT05917964

NCT04993690

NCT06978088

NCT05432713

NCT06126861

Action Inhibit “LP-168 is a small molecule inhibitor.” NCT04775745
Modality Small molecule “LP-168 is a small molecule inhibitor.” NCT04775745
1

CHEMBL5314539

Route Oral “LP-168 administered once or twice daily as a single agent dosed orally” NCT04775745
Target BTK “new generation Bruton Tyrosine Kinase inhibitor Rocbrutinib” NCT06251180