Drugs / BIIB094
last change Mar 2026 re-read 3 minutes ago

BIIB094

also known as ION859

Antisense oligonucleotide targets LRRK2

Developed for
Parkinson disease
Investigated by
Ionis Pharmaceuticals, Inc.

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03976349 Aug 2019 → Aug 2024 Parkinson disease Ionis Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as BIIB094 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03976349 ↗
Known as ION859 “BIIB094 (ION859), an antisense oligonucleotide, targets LRRK2 mRNA for degradation.” PMID 41876647 ↗ Mar 2026
Modality Antisense oligonucleotide “BIIB094 (ION859), an antisense oligonucleotide, targets LRRK2 mRNA for degradation.” PMID 41876647 ↗ Mar 2026
Target LRRK2 “targets LRRK2 mRNA for degradation.” PMID 41876647 ↗ Mar 2026