Drugs / RPCAR01
last change Jul 2026 re-read 3 minutes ago

RPCAR01

Cell therapy targets GPC3 via depletion

Developed for
hepatocellular carcinoma
Investigated by
Roswell Park Cancer Institute

Trials 1

20272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06968195 Jul 2026 → May 2028 hepatocellular carcinoma Roswell Park Cancer Institute Suspended No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as RPCAR01 “RPCAR01 is a genetically modified T cell (a part of the immune system) product that targets GPC3 and decreases the inhibition of T cells by a protein called transforming growth...” NCT06968195 ↗
Action Deplete “identify and kill GPC3 tumor cells” NCT06968195 ↗
Modality Cell therapy “RPCAR01 is a genetically modified T cell (a part of the immune system) product” NCT06968195 ↗
Route Intravenous “RPCAR01 CAR T cells IV over 15 minutes on day 1” NCT06968195 ↗
Target GPC3 “product that targets GPC3” NCT06968195 ↗