Drugs / XL102
last change May 2024 re-read 2 minutes ago

XL102

targets CDK7 via inhibition

Developed for
castration-resistant prostate carcinoma · hormone receptor-positive breast cancer · malignant epithelial tumor of ovary · triple-negative breast carcinoma
Investigated by
Exelixis

Trials 1 · a red edge is where a trial was stopped

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04726332 Feb 2021 → May 2024 castration-resistant prostate carcinoma, hormone receptor-positive breast cancer, malignant epithelial tumor of ovary, triple-negative breast carcinoma Exelixis Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as XL102 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04726332
Action Inhibit “XL102, a highly specific, orally bioavailable covalent inhibitor of CDK7.” PMID 37507802 Jul 2023
Route Oral “XL102 administered orally alone and in multiple combination regimens” NCT04726332
Target CDK7 “XL102, a highly specific, orally bioavailable covalent inhibitor of CDK7.” PMID 37507802 Jul 2023