Drugs / LauT-1
last change Mar 2025 re-read 3 minutes ago

LauT-1

Cell therapy

Developed for
metastatic melanoma · sarcoma
Investigated by
Centre Hospitalier Universitaire Vaudois

Trials 1

2026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06889766 Mar 2025 → Jun 2029 expected metastatic melanoma, sarcoma Centre Hospitalier Universitaire Vaudois Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as LauT-1 “the patients' own T-cells will be isolated, then genetically modified to express the I53F NY-ESO-1 TCR and expanded to generate the product "LauT-1", which is reinfused into...” NCT06889766 ↗
Action Deplete “thereby maximising the chance to detect and potentially eliminate NY-ESO-1 expressing tumor cells” NCT06889766 ↗
Modality Cell therapy “Ex vivo expanded autologous CD4+/CD8+ cells expressing the transgenic TCR I53F” NCT06889766 ↗
Route Intravenous “On D0, patients will receive NY-ESO-1 TCR T cell infusion, intravenously.” NCT06889766 ↗