Drugs / Tarloxotinib
last change Dec 2023 re-read 2 minutes ago

Tarloxotinib

also known as TH-4000
Developed for
non-small cell lung carcinoma · head and neck squamous cell carcinoma
Investigated by
Rain Oncology Inc · Medical University of South Carolina

Trials 3 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT05313009 Mar 2022 → Jul 2023 non-small cell lung carcinoma Medical University of South Carolina Terminated No outcome recorded
Phase 22 trials
Phase 2 NCT03805841 Mar 2019 → Apr 2021 non-small cell lung carcinoma Rain Oncology Inc Terminated No outcome recorded
Phase 2 NCT02449681 Aug 2015 → Jan 2017 head and neck squamous cell carcinoma Rain Oncology Inc Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as tarloxotinib ClinicalTrials.gov intervention name — accepted as the source's own label NCT03805841
2

NCT02449681

NCT05313009

Known as TH-4000 TH-4000 (Tarloxotinib)” NCT02449681
Action Inhibit “an irreversible pan-ErbB tyrosine kinase inhibitor” PMID 35435625 Apr 2022
Route Intravenous “will be administered by IV infusion over 60 minutes” NCT02449681