Drugs / THRV-1268
last change Mar 2026 re-read 3 minutes ago

THRV-1268

targets SGK1 via inhibition

Developed for
long QT syndrome 2
Investigated by
Thryv Therapeutics, Inc.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07186946 Sep → Oct 2025 heart failure Thryv Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT06507839 May → Nov 2024 atrial fibrillation Thryv Therapeutics, Inc. Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT07277582 Mar 2026 → Jun 2027 expected long QT syndrome 2 Thryv Therapeutics, Inc. Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as THRV-1268 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07186946 ↗
2

NCT07277582 ↗

NCT06507839 ↗

Action Inhibit “(SGK-1) inhibitor” NCT06507839 ↗
Route Oral “5 dosing cohorts will receive a single oral dose of THRV-1268.” NCT06507839 ↗
Target SGK1 “THRV-1268 a serum glucocorticoid regulated kinase 1 (SGK-1) inhibitor” NCT06507839 ↗