Drugs / BUTYRIC ACID
BUTYRIC ACID
also known as
Butyrate · Butanoic acid · Butyricum acidum · FEMA NO. 2221 · N-butanoic acid · N-butyric acid · Normal butyric acid · NSC-8415
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT05218850 | Jun 2022 → Jun 2027 expected | ulcerative colitis | Children's Hospital Los Angeles | Recruiting | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT01536483 | Feb 2012 → Mar 2016 | — | Nantes University Hospital | Terminated | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT03660176 | Jan 2019 → Jan 2024 | Hirschsprung disease | Assistance Publique Hopitaux De Marseille | Unknown | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00726817 | Dec 2007 → Feb 2008 | — | Maastricht University Medical Center | Completed | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT04259060 Comparator | Jan 2024 → Aug 2025 | ulcerative colitis | Joshua Korzenik | Withdrawn | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT01983046 Comparator | Sep 2013 → Feb 2014 | obesity disorder, type 2 diabetes mellitus | Maastricht University Medical Center | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | BUTYRIC ACID | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | Butanoic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | Butyrate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00726817 ↗ |
| Known as | Butyricum acidum | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | FEMA NO. 2221 | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | N-butanoic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | N-butyric acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | Normal butyric acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Known as | NSC-8415 | ChEMBL registry synonym — accepted as the source's own label CHEMBL14227 ↗ |
| Modality | Small molecule | “Butyrate is a short chain fatty acid produced in the colon by the microbiota” NCT01536483 ↗ |
| Route | Other | “received an enema once daily for one week containing either placebo (saline), 50mM butyrate or 100mM of butyrate” NCT00726817 ↗ |