Drugs / AAV-hTERT
last change Jan 2021 re-read 3 minutes ago

AAV-hTERT

also known as LGT

Gene therapy (AAV / viral vector) targets TERT

Developed for
Alzheimer disease · limb ischemia
Investigated by
Libella Gene Therapeutics

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04133649 Oct 2019 → Jan 2021 — Libella Gene Therapeutics Unknown No outcome recorded
Phase 1 NCT04133454 Oct 2019 → Jan 2021 Alzheimer disease Libella Gene Therapeutics Unknown No outcome recorded
Phase 1 NCT04110964 Sep 2019 → Dec 2020 limb ischemia Libella Gene Therapeutics Unknown No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as AAV-hTERT ClinicalTrials.gov intervention name — accepted as the source's own label NCT04133649 ↗
2

NCT04133454 ↗

NCT04110964 ↗

Known as LGT “subjects will receive a single LGT (AAV-hTERT) treatment via IV administration” NCT04133649 ↗
Action Restore “Investigate LGT's ability to deliver hTERT to human cells and lengthen telomeres.” NCT04110964 ↗
Modality Gene therapy (AAV / viral vector) “This study will entail treating subjects with hTERT delivered via transduction using AAV.” NCT04110964 ↗
Route Intravenous “via IV administration” NCT04110964 ↗
Target TERT “Using gene therapy to express active telomerase (hTERT) in human cells” NCT04110964 ↗