Drugs / FPI-2265
last change Jul 2026 re-read 2 minutes ago

FPI-2265

also known as AZD2265 · 225Ac-PSMA-I&T

Small molecule

Developed for
castration-resistant prostate carcinoma · metastatic prostate carcinoma · prostate carcinoma
Investigated by
Fusion Pharmaceuticals Inc. · AstraZeneca

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT07590934 Jun 2026 → Sep 2029 expected metastatic prostate carcinoma AstraZeneca Recruiting No outcome recorded
Phase 23 trials
Phase 2 NCT06909825 Feb 2025 → May 2027 expected metastatic prostate carcinoma Fusion Pharmaceuticals Inc. Active not recruiting No outcome recorded
Phase 2 NCT06402331 Mar 2024 → Dec 2026 expected castration-resistant prostate carcinoma Fusion Pharmaceuticals Inc. Active not recruiting No outcome recorded
Phase 2 NCT05219500 Dec 2021 → May 2025 overdue castration-resistant prostate carcinoma Fusion Pharmaceuticals Inc. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07611110 May 2026 → Feb 2029 expected prostate carcinoma AstraZeneca Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as FPI-2265 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05219500
2

NCT06402331

NCT06909825

Known as 225Ac-PSMA-I&T “FPI-2265 (225Ac-PSMA-I&T) and Olaparib for Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)” NCT06909825
Known as AZD2265 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07590934
1

NCT07611110

Modality Small molecule Small molecule capable of binding to the domain of PSMA radiolabeled with Ac225” NCT05219500
Route Intravenous “FPI-2265 (Dose A intravenously \[IV\] every six weeks)” NCT06909825