Drugs / TGF-betaR2KO/IL13R-alpha2-CAR T cells
last change Jun 2025 re-read 3 minutes ago

TGF-betaR2KO/IL13R-alpha2-CAR T cells

Cell therapy

Developed for
astrocytoma, IDH-mutant, grade 3 · astrocytoma, IDH-mutant, grade 4 · glioblastoma
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 1

20262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06815029 Jun 2025 → Oct 2030 expected astrocytoma, IDH-mutant, grade 3, astrocytoma, IDH-mutant, grade 4, glioblastoma City of Hope Medical Center Recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TGF-betaR2KO/IL13R-alpha2-CAR T cells “Given autologous TGF-betaR2KO/IL13R-alpha2-CAR T cells intracranially” NCT06815029 ↗
Modality Cell therapy “CAR T-cell therapy is a type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack tumor cells.” NCT06815029 ↗
Route Other “intracranially” NCT06815029 ↗