Drugs / Neostigmine Methylsulfate
last change Jul 2023 re-read 2 minutes ago

Neostigmine Methylsulfate

Small molecule

Developed for
intracranial hypotension
Investigated by
Alexandria University · Fayoum University · Kasr El Aini Hospital

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) BLOXIVERZ 2013-05-31 fda.gov

Trials 1 · a red edge is where a trial was stopped

today
US approved 2013
NCT05289323 · Ph 4
20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT05289323 Apr 2022 → Jul 2023 intracranial hypotension Alexandria University Completed No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT03997006 Comparator Jan 2019 → Jan 2020 intracranial hypotension Damanhour Teaching Hospital Completed No outcome recorded
Phase 4 NCT03587441 Comparator Aug 2018 → Feb 2019 intracranial hypotension Fayoum University Hospital Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Neostigmine Methylsulfate ClinicalTrials.gov intervention name — accepted as the source's own label NCT03997006
2

NCT05289323

NCT03587441

Action Inhibit “reversibly inhibits the enzyme Acetylcholine esterase (AChE)” NCT03587441
Modality Small molecule “Neostigmine methylsulfate is a synthetic carbamic acid ester” NCT03587441
Route Intrathecal “Neostigmine Methylsulfate intrathecalNCT03587441