Drugs / 1-(4-(DIMETHYLAMINO)PIPERIDIN-1-YL)-3-HYDROXY-3-(1-METHYL-1H-IMIDAZOL-2-YL)PROPAN-1-ONE, (S)-
last change Dec 2021 re-read 3 minutes ago

1-(4-(DIMETHYLAMINO)PIPERIDIN-1-YL)-3-HYDROXY-3-(1-METHYL-1H-IMIDAZOL-2-YL)PROPAN-1-ONE, (S)-

also known as TRK-750

Small molecule

Developed for
chemotherapy-induced neuropathy · neuropathy, painful
Investigated by
Toray Industries, Inc

Trials 2

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03346330 Nov 2017 → Aug 2018 neuropathy, painful Toray Industries, Inc Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04282590 Apr 2020 → Dec 2021 chemotherapy-induced neuropathy Toray Industries, Inc Withdrawn No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as 1-(4-(DIMETHYLAMINO)PIPERIDIN-1-YL)-3-HYDROXY-3-(1-METHYL-1H-IMIDAZOL-2-YL)PROPAN-1-ONE, (S)- ChEMBL registry synonym — accepted as the source's own label CHEMBL6068564 ↗
Known as TRK-750 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04282590 ↗
1

NCT03346330 ↗

Modality Small molecule — CHEMBL6068564 ↗
Route Oral “ascending oral doses of TRK-750” NCT03346330 ↗