Drugs / GREZIPRUBART
last change 2 days ago re-read 3 minutes ago

GREZIPRUBART

also known as STSA-1002

Monoclonal antibody

Developed for
acute respiratory distress syndrome · adult acute respiratory distress syndrome
Investigated by
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT05702983 Jan → Apr 2023 anti-neutrophil cytoplasmic antibody-associated vasculitis Staidson (Beijing) Biopharmaceuticals Co., Ltd Completed No outcome recorded
Phase 1 NCT05559125 Nov 2022 → Mar 2024 — Staidson (Beijing) Biopharmaceuticals Co., Ltd Terminated No outcome recorded
Phase 1 NCT05497635 Oct 2022 → Apr 2023 — Staidson (Beijing) Biopharmaceuticals Co., Ltd Completed No outcome recorded
Phase 1 NCT05166837 Jan 2022 → Jan 2023 — Staidson (Beijing) Biopharmaceuticals Co., Ltd Completed No outcome recorded
Phase 1 NCT05032144 Sep 2021 → Mar 2022 — Staidson (Beijing) Biopharmaceuticals Co., Ltd Completed No outcome recorded
Phase 1/21 trial · 1 missed
Phase 1/2 NCT06038916 Dec 2023 → Mar 2025 adult acute respiratory distress syndrome Staidson (Beijing) Biopharmaceuticals Co., Ltd Completed Missed primary
Phase 31 trial
Phase 3 NCT07208591 Oct 2025 → Jul 2026 overdue acute respiratory distress syndrome Staidson (Beijing) Biopharmaceuticals Co., Ltd Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as GREZIPRUBART ChEMBL registry synonym — accepted as the source's own label CHEMBL6068253 ↗
Known as STSA-1002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05702983 ↗
6

NCT07208591 ↗

NCT06038916 ↗

NCT05166837 ↗

NCT05559125 ↗

NCT05497635 ↗

NCT05032144 ↗

Action Inhibit “STSA-1002 was a high-affinity, selective anti-human C5a monoclonal antibody blocking C5a-mediated reactive oxygen species (ROS) production.” PMID 42394970 ↗ Jun 2026
Modality Monoclonal antibody “STSA-1002 is a fully human monoclonal antibody” PMID 42394970 ↗ Jun 2026
Route Intravenous “Intravenous injection” NCT05032144 ↗