Drugs / NU-0129
last change Aug 2020 re-read 3 minutes ago

NU-0129

Oligonucleotide (other) targets BCL2L12

Developed for
gliosarcoma
Investigated by
National Cancer Institute (NCI) · Northwestern University

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT03020017 May 2017 → Sep 2018 gliosarcoma Northwestern University Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as NU-0129 “A Phase 0 First-In-Human Study Using NU-0129: A Spherical Nucleic Acid (SNA) Gold Nanoparticle Targeting BCL2L12 in Recurrent Glioblastoma Multiforme or Gliosarcoma Patients” NCT03020017 ↗
Modality Oligonucleotide (other) “The SNA consists of nucleic acids arranged on the surface of a small spherical gold nanoparticle.” NCT03020017 ↗
Route Intravenous “Patients receive NU-0129 intravenously (IV) over 20-50 minutes” NCT03020017 ↗
Target BCL2L12 “Once within the tumor, the nucleic acid component is able to target a gene called Bcl2L12” NCT03020017 ↗