Drugs / Oxyntomodulin
last change Mar 2018 re-read 3 minutes ago

Oxyntomodulin

also known as OXM

Protein / enzyme biologic

Developed for
type 2 diabetes mellitus
Investigated by
Merck Sharp & Dohme LLC

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01373450 Jun → Jul 2011 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed Met primary
Phase 1 NCT01055340 Apr → May 2010 obesity disorder Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Oxyntomodulin ClinicalTrials.gov intervention name — accepted as the source's own label NCT01055340 ↗
1

NCT01373450 ↗

Known as OXM “Oxyntomodulin (OXM), an enteroendocrine hormone, causes appetite suppression, increased energy expenditure, and weight loss in obese humans via activation of GLP-1 and glucagon...” PMID 29545266 ↗ Mar 2018
Action Activate “via activation of GLP-1 and glucagon receptors” PMID 29545266 ↗ Mar 2018
Modality Protein / enzyme biologic — CHEMBL2401865 ↗
Route Intravenous “Single infusion of OXM 3.0 pmol/kg/min by IV” NCT01055340 ↗