Drugs / VAX125
last change May 2011 re-read 3 minutes ago

VAX125

also known as STF2.HA1(SI)

Vaccine targets TLR5 via activation

Developed for
influenza
Investigated by
VaxInnate Corporation · University of Rochester

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00730457 Jul 2008 → Mar 2009 influenza VaxInnate Corporation Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00966238 Sep 2009 → Apr 2010 influenza VaxInnate Corporation Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as VAX125 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00730457 ↗
1

NCT00966238 ↗

Known as STF2.HA1(SI) “STF2.HA1(SI) (VAX125), which is a recombinant fusion protein that consists of Salmonella typhimurium flagellin type 2 (STF2), a Toll-like receptor 5 (TLR5) ligand, fused at its...” NCT00966238 ↗
Action Activate “TLR-5 agonist” PMID 21596084 ↗ May 2011
Modality Vaccine “recombinant hemagglutinin influenza-flagellin fusion vaccine” PMID 20969925 ↗ Oct 2010
Route Intramuscular “administered intramuscularly (im)” PMID 20969925 ↗ Oct 2010
Target TLR5 “a Toll-like receptor 5 (TLR5) ligand” NCT00966238 ↗