Drugs / IMSAPEPIMUT
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT03562871 | Aug 2018 → Feb 2021 | non-small cell lung carcinoma | IO Biotech | Completed | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT05280314 | Dec 2023 → Apr 2025 overdue | head and neck squamous cell carcinoma, melanoma | IO Biotech | Recruiting | No outcome recorded |
| Phase 2 | NCT05912244 | Jun 2023 → Jun 2027 expected | melanoma | Memorial Sloan Kettering Cancer Center | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05077709 | Apr 2022 → Nov 2025 | head and neck squamous cell carcinoma, non-small cell lung carcinoma, urothelial carcinoma | IO Biotech | Completed | No outcome recorded |
| Phase 2 | NCT04445064 | Aug 2020 → Jun 2024 | hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, oral cavity squamous cell carcinoma, oropharynx squamous cell carcinoma | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Terminated | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | IMSAPEPIMUT | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068401 ↗ |
| Known as | IO102 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03562871 ↗ |
| Action | Activate | “Activation of IDO or PD-L1 specific T-cells through vaccination with the IDO and PD-L1 peptides (IO102-IO103) will boost natural killing of cancer cells and counteract immune...” NCT05077709 ↗ |
| Modality | Peptide | “Activation of IDO or PD-L1 specific T-cells through vaccination with the IDO and PD-L1 peptides (IO102-IO103) will boost natural killing of cancer cells and counteract immune...” NCT05077709 ↗ |
| Route | Subcutaneous | “administered subcutaneously (SC)” NCT03562871 ↗ |