Drugs / PF-06763809
last change Sep 2020 re-read 2 minutes ago

PF-06763809

targets RORC via inhibition

Developed for
psoriasis
Investigated by
Pfizer

Trials 1 · a red edge is where a trial was stopped

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03469336 Apr 2018 → Mar 2019 psoriasis Pfizer Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as PF-06763809 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03469336
Action Inhibit “The RORC2 inhibitor PF-06763809 has been hypothesized to inhibit IL-17A production in T-helper 17 (Th17) cells, thereby reducing psoriasis symptoms.” PMID 32767679 Sep 2020
Route Topical “Participants received each of the following six treatments once daily for 18 days: three topical doses (2.3%, 0.8%, 0.23%) of PF-06763809, a vehicle and two active comparators...” PMID 32767679 Sep 2020
Target RORC “The RORC2 inhibitor PF-06763809 has been hypothesized to inhibit IL-17A production in T-helper 17 (Th17) cells, thereby reducing psoriasis symptoms.” PMID 32767679 Sep 2020