Drugs / TEZAMPANEL ANHYDROUS
last change Nov 2025 re-read 3 minutes ago

TEZAMPANEL ANHYDROUS

also known as TEZAMPANEL · LY-293,558 · NGX-424 · Tezampanel hydrate · TZP

Small molecule

Developed for
migraine disorder · substance-related disorder
Investigated by
Indiana University · Proniras Corporation · TorreyPines Therapeutics

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06538558 Oct 2024 → Oct 2025 overdue substance-related disorder Proniras Corporation Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT00567086 Oct 2006 → Aug 2007 migraine disorder TorreyPines Therapeutics Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TEZAMPANEL ANHYDROUS ChEMBL registry synonym — accepted as the source's own label CHEMBL14935 ↗
Known as LY-293,558 ChEMBL registry synonym — accepted as the source's own label CHEMBL14935 ↗
Known as NGX-424 ChEMBL registry synonym — accepted as the source's own label CHEMBL14935 ↗
Known as TEZAMPANEL ClinicalTrials.gov intervention name — accepted as the source's own label NCT00567086 ↗
1

NCT06538558 ↗

Known as Tezampanel hydrate ChEMBL registry synonym — accepted as the source's own label CHEMBL14935 ↗
Known as TZP “This study is examining the use of Tezampanel (TZP) for treatment of Opioid Withdrawal Syndrome (OWS) in participants with Opioid Use Disorder (OUD).” NCT06538558 ↗
Modality Small molecule — CHEMBL14935 ↗
Route Subcutaneous “single sc administration of TEZAMPANEL” NCT00567086 ↗