Drugs / Loteprednol
last change Nov 2017 re-read 2 minutes ago

Loteprednol

also known as Lotemax

Other / unclassified

Developed for
bacterial conjunctivitis · blepharitis · keratitis · cataract
Investigated by
Adapt Produtos Oftalmológicos Ltda.

Trials 1 · a red edge is where a trial was stopped

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01721694 Dec 2012 → Mar 2013 bacterial conjunctivitis, blepharitis, keratitis Adapt Produtos Oftalmológicos Ltda. Withdrawn No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT07671222 Comparator Dec 2026 → Mar 2028 expected Sjogren syndrome, dry eye syndrome Instituto de Oftalmología Fundación Conde de Valenciana Not yet recruiting No outcome recorded
Phase 44 trials
Phase 4 NCT02974387 Comparator Apr → Aug 2017 Dr Salouti Eye Research Center Unknown No outcome recorded
Phase 4 NCT01456780 Comparator Aug 2011 → Mar 2013 blepharitis Massachusetts Eye and Ear Infirmary Completed No outcome recorded
Phase 4 NCT01193504 Comparator Sep 2010 → Oct 2012 cataract Innovative Medical Unknown No outcome recorded
Phase 4 NCT00817557 Comparator Jan → Jun 2009 Hom, Milton M., OD, FAAO Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Loteprednol “Randomized, Masked Comparison of Bromfenac and Besifloxacin BID With Either Prednisolone BID or Loteprednol 0.5% BID for Prevention of Retinal Thickening and CME Following...” NCT01193504
5

NCT00817557

NCT01456780

NCT02974387

NCT01721694

NCT07671222

Known as Lotemax “Loteprednol (Lotemax)” NCT02974387
Action Inhibit “Loteprednol inhibits processes in the body that cause inflammation.” NCT01456780
Modality Other / unclassified “steroid agents” NCT02974387
Route Topical “Lotemax eye drops” NCT01193504