Drugs / Anfibatide
last change Nov 2021 re-read 3 minutes ago

Anfibatide

also known as Agkisacucetin

Protein / enzyme biologic targets GP1BA via inhibition

Developed for
acquired thrombotic thrombocytopenic purpura · myocardial infarction · ST-elevation myocardial infarction
Investigated by
Lee's Pharmaceutical Limited

Trials 3

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04404790 Sep 2020 → Mar 2021 — Lee's Pharmaceutical Limited Suspended No outcome recorded
Phase 1 NCT01588132 Sep 2010 → Mar 2011 blood coagulation disease, coronary artery disorder Lee's Pharmaceutical Limited Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04021173 Jul 2019 → Jul 2021 acquired thrombotic thrombocytopenic purpura Lee's Pharmaceutical Limited Unknown No outcome recorded
Comparator or background therapy2 trials
Phase 1/2 NCT01585259 Comparator Jul 2012 → Dec 2014 myocardial infarction Lee's Pharmaceutical Limited Completed No outcome recorded
Phase 2 NCT02495012 Comparator Aug 2015 → Mar 2016 ST-elevation myocardial infarction Lee's Pharmaceutical Limited Unknown No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Anfibatide ClinicalTrials.gov intervention name — accepted as the source's own label NCT04021173 ↗
4

NCT02495012 ↗

NCT01585259 ↗

NCT04404790 ↗

NCT01588132 ↗

Known as Agkisacucetin ChEMBL registry synonym — accepted as the source's own label CHEMBL4297694 ↗
Action Inhibit “This study shows that intravenous administration of the platelet receptor GP Ib antagonist anfibatide is feasible and safe to inhibit platelet aggregation without increasing...” PMID 34478577 ↗ Sep 2021
1

“Platelet glycoprotein Ib alpha chain antagonist” CHEMBL4297694 ↗

Modality Protein / enzyme biologic — CHEMBL4297694 ↗
Route Intravenous “intravenous administration of the platelet receptor GP Ib antagonist anfibatide” PMID 34478577 ↗ Sep 2021
Target GP1BA “Platelet glycoprotein Ib alpha chain antagonist” CHEMBL4297694 ↗