Drugs / Restylane-L®
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04169308 | Jan 2019 → Jul 2020 | nose, anomalous shape of | DeNova Research | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT03460158 | Aug 2020 → Feb 2024 | — | University of Pennsylvania | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 0 | NCT03313934 Background | Nov 2017 → Nov 2018 | — | Rejuva Medical Aesthetics | Unknown | No outcome recorded |
News releases announcing trial results or a regulatory action · 2
| Date | Issuer | Release |
|---|---|---|
| 2026-02-25 | Galderma R&D | Regulatory Galderma announces triple approval of new state-of-the-art Restylane® syringe in the EU, the U.S., and Canada, reaffirming the company’s position at the forefront of Injectable Aesthetics galderma.com ↗
Regulatory authorities in the European Union (EU), the United States (U.S.), and Canada have approved a new state-of-the-art Restylane® syringe for use with a range of Restylane NASHA® lidocaine products in multiple indications in the face and in the hands |
| 2021-11-22 | Galderma R&D | Results Galderma leads oral presentation on hyaluronic acid filler safety insights at ASDS 2021 Annual Meeting galderma.com ↗
Leveraging reports from the Manufacturer and User Facility Device Experience (MAUDE) database, the surveillance study analyzed delayed-onset (≥14 days) adverse events (AEs) of interest (inflammatory and non-inflammatory nodules, hypersensitivity, granulomas) for HA fillers FDA-approved between 2016-2020. |
All press releases naming this drug 2 releases
Evidence & citations 3 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Restylane-L | “The use of Restylane-L to volumize the tear trough has been well documented.” NCT03313934 ↗ |
| Modality | Other / unclassified | “using HA fillers: Restylane-L in nasolabial folds and marionette lines” PMID 40178806 ↗ Apr 2025 |
| Route | Other | “dermal implantation” NCT03460158 ↗ |