Drugs / sulphadoxine-pyrimethamine

Trials 11

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00959517 Jul 2001 → Jun 2005 Plasmodium falciparum malaria London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT00146783 Jun 2004 → Feb 2007 malaria London School of Hygiene and Tropical Medicine Completed No outcome recorded
Phase 31 trial · 1 met primary
Phase 3 NCT00131703 Mar 2003 → Mar 2005 malaria, pregnancy disorder London School of Hygiene and Tropical Medicine Completed Met primary
Phase not applicable8 trials
— NCT06182176 May → Nov 2024 Nematoda infectious disease, malaria, schistosomiasis London School of Hygiene and Tropical Medicine Unknown No outcome recorded
— NCT02758353 Apr → Nov 2015 malaria, pregnancy disorder with abortive outcome JSI Research & Training Institute, Inc. Completed No outcome recorded
— NCT01707199 Oct 2012 → Jan 2014 Plasmodium falciparum malaria University of Oxford Completed No outcome recorded
— NCT00259142 Nov 2005 anemia, malaria DBL -Institute for Health Research and Development Terminated No outcome recorded
— NCT00301054 Jun 2005 → Apr 2006 anemia Ghana Health Services Completed No outcome recorded
— NCT00157859 Apr → Sep 2004 Plasmodium falciparum malaria, Plasmodium vivax malaria Menzies School of Health Research Completed No outcome recorded
— NCT00118027 May 2003 → Jun 2007 anemia, malaria London School of Hygiene and Tropical Medicine Completed No outcome recorded
— NCT00140517 Oct 2002 → Jun 2007 Plasmodium falciparum malaria, anemia London School of Hygiene and Tropical Medicine Completed No outcome recorded
Comparator or background therapy3 trials
Phase 3 NCT03208179 Comparator Mar 2018 → Mar 2020 malaria, pregnancy disorder Liverpool School of Tropical Medicine Completed Missed primary
Phase 3 NCT01053325 Comparator Sep 2010 → Dec 2012 HIV infectious disease, malaria Institute of Tropical Medicine, Belgium Completed No outcome recorded
— NCT00285662 Comparator Jun 2006 → May 2010 anemia, malaria Papua New Guinea Institute of Medical Research Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 16 sources stand behind the page.

FieldValueCited text
Known as sulphadoxine-pyrimethamine “The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria” NCT02758353 ↗
13

“Intermittent preventive treatment with sulphadoxine-pyrimethamine” NCT01053325 ↗

NCT00959517 ↗

NCT03208179 ↗

NCT06182176 ↗

NCT00301054 ↗

NCT00131703 ↗

NCT00285662 ↗

NCT00157859 ↗

NCT00146783 ↗

NCT01707199 ↗

Show 3 more sources

Known as sulfadoxine-pyrimethamine “The use of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment in pregnancy (IPTp) is threatened by the spread of resistance to SP.” PMID 18752443 ↗ Oct 2008
1

“sulfadoxine-pyrimethamine (SP) (25 mg/kg and 1.25 mg/kg) plus amodiaquine (AQ) (10 mg/kg, 3 d, n = 374)” PMID 22479155 ↗ Mar 2012

Modality Small molecule “Sulphadoxine-pyrimethamine (SP) is a fixed combination of a long-acting sulfonamide and the antifolate pyrimethamine.” NCT01707199 ↗