Drugs / masoprocol
masoprocol
also known as
Actinex · CHX-100 · Dihydronorguaiaretic acid · Dinorguaiaretic acid, dihydro- · Insm-18 · MESO-NDGA · Meso-nordihydroguaiaretic acid · NDGA · +5 more
Small molecule targets ERBB2, IGF1R via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ACTINEX | — | 1992-09-04 | fda.gov ↗ |
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT00313534 | Jun 2005 → Oct 2006 | prostate cancer | University of California, San Francisco | Terminated | No outcome recorded |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | masoprocol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00313534 ↗ |
| Known as | Actinex | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | CHX-100 | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Dihydronorguaiaretic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Dinorguaiaretic acid, dihydro- | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Insm-18 | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | MESO-NDGA | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Meso-nordihydroguaiaretic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | NDGA | “nordihydroguaiaretic acid (NDGA)” NCT00313534 ↗ |
| Known as | Nordihydroguaiaretate | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Nordihydroguiaretic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | NSC-4291 | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | NSC-682984 | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Known as | Oristar nhga | ChEMBL registry synonym — accepted as the source's own label CHEMBL313972 ↗ |
| Action | Inhibit | “Receptor protein-tyrosine kinase erbB-2 inhibitor” CHEMBL313972 ↗1“Insulin-like growth factor I receptor inhibitor” CHEMBL313972 ↗ |
| Modality | Small molecule | — CHEMBL313972 ↗ |
| Route | Oral | “Patients receive oral nordihydroguaiaretic acid (NDGA) twice daily” NCT00313534 ↗ |
| Target | ERBB2 | “Receptor protein-tyrosine kinase erbB-2 inhibitor” CHEMBL313972 ↗ |
| Target | IGF1R | “Insulin-like growth factor I receptor inhibitor” CHEMBL313972 ↗ |