Drugs / MK-4721
last change Nov 2015 re-read 3 minutes ago

MK-4721

also known as AGS-1C4D4 · AGS-PSCA

targets PSCA via inhibition

Developed for
pancreatic ductal adenocarcinoma · prostate cancer
Investigated by
Agensys, Inc. · Astellas Pharma Inc

Trials 3

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00519233 Sep 2007 → Sep 2009 prostate cancer Astellas Pharma Inc Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01608711 Aug 2012 → Nov 2015 pancreatic ductal adenocarcinoma Agensys, Inc. Completed No outcome recorded
Phase 2 NCT00902291 Apr 2009 → Apr 2012 pancreatic ductal adenocarcinoma Astellas Pharma Inc Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MK-4721 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109548 ↗
Known as AGS-1C4D4 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00519233 ↗
2

NCT01608711 ↗

NCT00902291 ↗

Known as AGS-PSCA ChEMBL registry synonym — accepted as the source's own label CHEMBL2109548 ↗
Action Inhibit “Prostate stem cell antigen inhibitor” CHEMBL2109548 ↗
Route Intravenous “IV infusion” NCT00902291 ↗
Target PSCA “Prostate stem cell antigen inhibitor” CHEMBL2109548 ↗