Drugs / LY3113593
last change Mar 2019 re-read 3 minutes ago

LY3113593

Monoclonal antibody targets BMP6 via inhibition

Investigated by
Eli Lilly and Company

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02604160 Nov 2015 → Jun 2016 chronic kidney disease Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT02144285 Jun 2014 → Aug 2015 chronic renal failure syndrome Eli Lilly and Company Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as LY3113593 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02144285 ↗
1

NCT02604160 ↗

Action Inhibit “LY3113593 specifically blocked BMP6 binding to its receptor” PMID 30677788 ↗ Mar 2019
Modality Monoclonal antibody “monoclonal antibodies, LY3113593 and LY2928057, targeting BMP6 and ferroportin respectively, were tested in CKD patients.” PMID 30677788 ↗ Mar 2019
Route Intravenous “Administered IV” NCT02144285 ↗
Target BMP6 “monoclonal antibodies, LY3113593 and LY2928057, targeting BMP6 and ferroportin respectively, were tested in CKD patients.” PMID 30677788 ↗ Mar 2019