Drugs / Olesoxime
Olesoxime
also known as
TRO19622 · 4-cholest-en-3-one, oxime · Cholest-4-en-3-one, oxime · NSC-21311 · Olesoxima · TRO19622 (olesoxime)
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT02835976 | Jul → Sep 2014 | — | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT01808885 | Apr 2013 → Jan 2014 | relapsing-remitting multiple sclerosis | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 25 trials | ||||||
| Phase 2 | NCT02628743 | Jan 2016 → Dec 2018 | spinal muscular atrophy | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2 | NCT01302600 | Nov 2010 → Oct 2013 | spinal muscular atrophy, type II, spinal muscular atrophy, type III | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2 | NCT00876538 | Mar 2009 → Sep 2010 | chemotherapy-induced neuropathy | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2 | NCT00666016 | Apr 2008 → Feb 2009 | metabolic dysfunction-associated steatohepatitis | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2 | NCT00496457 | May 2007 → Dec 2008 | diabetic polyneuropathy | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT01285583 | Oct 2010 → Mar 2012 | amyotrophic lateral sclerosis | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00868166 | Apr 2009 → Sep 2011 | amyotrophic lateral sclerosis | Hoffmann-La Roche | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | olesoxime | “Each patient will be treated with olesoxime (TRO19622) until the results of the double-blind trial become available with a maximum of 15 months.” NCT01285583 ↗ |
| Known as | 4-cholest-en-3-one, oxime | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545254 ↗ |
| Known as | Cholest-4-en-3-one, oxime | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545254 ↗ |
| Known as | NSC-21311 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545254 ↗ |
| Known as | Olesoxima | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545254 ↗ |
| Known as | TRO19622 | “Phase II, Multicenter, Randomized, Adaptive, Double-blind, Placebo Controlled Study to Assess Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Year Old Spinal Muscular...” NCT01302600 ↗5“Capsules of TRO19622 (125 mg)- Once a day before noon meal during 6 weeks” NCT00496457 ↗ “olesoxime (TRO19622)” NCT01808885 ↗ “Olesoxime (TRO19622)” NCT00876538 ↗ |
| Known as | TRO19622 (olesoxime) | “TRO19622 (olesoxime)” NCT01808885 ↗ |
| Modality | Small molecule | — CHEMBL3545254 ↗ |
| Route | Oral | “TRO19622 administered PO daily for 6 weeks” NCT00496457 ↗ |