Drugs / Testolactone
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TESLAC | — | 1969-06-03 | fda.gov ↗ |
Trials 3 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT00001202 | Jan 1985 → Jan 2004 | precocious puberty | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Completed | No outcome recorded |
| Phase 2 | NCT00001181 | Oct 1982 → May 2003 | peripheral precocious puberty, polyostotic fibrous dysplasia | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00001521 | Jun 1995 → Apr 2024 | congenital adrenal hyperplasia | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Testolactone | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00001181 ↗ |
| Known as | Fludestrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Known as | NSC-23759 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Known as | SQ 9538 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Known as | Teolit | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Known as | Teslac | “Testolactone (Teslac) to inhibit aromatase, the last step of estrogen biosynthesis.” NCT00001202 ↗ |
| Known as | Testolactona | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Known as | Testolactone ciii | ChEMBL registry synonym — accepted as the source's own label CHEMBL1571 ↗ |
| Action | Inhibit | “Testolactone inhibits aromatase” NCT00001181 ↗1“Cytochrome P450 19A1 inhibitor” CHEMBL1571 ↗ |
| Modality | Small molecule | — CHEMBL1571 ↗ |
| Route | Oral | “testolactone - 20mg/ kg/day orally” NCT00001521 ↗ |
| Target | CYP19A1 | “Cytochrome P450 19A1 inhibitor” CHEMBL1571 ↗ |