Drugs / Tianeptine
Tianeptine
also known as
JNJ-39823277 · Gas station heroin · S-1574 · Stablon · Tianeptina · TNX-601 ER · TPI 1062
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT02103985 | May → Jun 2009 | — | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Completed | No outcome recorded |
| Phase 1 | NCT02049697 | Apr → May 2009 | — | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Completed | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT05686408 | Mar → Sep 2023 | major depressive disorder | Tonix Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 2 | NCT06012552 | Feb 2023 → Apr 2027 expected | nervous system disorder | Military Institute od Medicine National Research Institute | Recruiting | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT04249596 | Oct 2020 → Aug 2024 | — | Jonathan A. Javitch, MD, PhD | Terminated | No outcome recorded |
| Phase 4 | NCT01309776 | Mar 2011 → Sep 2012 | major depressive disorder | Samsung Medical Center | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT04145076 | Dec 2014 → Feb 2023 | autism spectrum disorder | King's College London | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT00879372 Comparator | Mar 2009 → May 2013 | bipolar disorder | Hospital de Clinicas de Porto Alegre | Unknown | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT05935059 Comparator | Jun 2023 → Mar 2025 | myofascial pain syndrome | National Cancer Institute, Egypt | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tianeptine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04249596 ↗ |
| Known as | Gas station heroin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1289110 ↗ |
| Known as | JNJ-39823277 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02049697 ↗ |
| Known as | S-1574 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1289110 ↗ |
| Known as | Stablon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1289110 ↗ |
| Known as | Tianeptina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1289110 ↗ |
| Known as | TNX-601 ER | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05686408 ↗ |
| Known as | TPI 1062 | “Absorption, Metabolism, and Excretion of 14C-JNJ-39823277 (TPI 1062) After a Single Oral Dose in Healthy Male Subjects” NCT02049697 ↗ |
| Action | Activate | “Work in our laboratories has shown that tianeptine acts as a selective agonist of MOR” NCT04249596 ↗ |
| Modality | Small molecule | — CHEMBL1289110 ↗ |
| Route | Oral | “tianeptine is approved to be used orally in humans” NCT00879372 ↗ |