Drugs / A27.15
last change Feb 2001 re-read 3 minutes ago

A27.15

Monoclonal antibody targets TFRC via inhibition

Developed for
leukemia · myelodysplastic syndrome · myeloproliferative neoplasm · plasma cell neoplasm · precancerous condition
Investigated by
National Cancer Institute (NCI) · University of Arizona

Trials 1

199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00003082 Dec 1997 → Feb 2001 leukemia, myelodysplastic syndrome, myeloproliferative neoplasm, plasma cell neoplasm +1 University of Arizona Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as A27.15 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00003082 ↗
Action Inhibit “Transferrin receptor protein 1 antagonist” CHEMBL2109494 ↗
Modality Monoclonal antibody “Combined Murine IgG Monoclonal Anti-Transferrin Receptor Antibodies E2.3 and A27.15” NCT00003082 ↗
Route Intravenous “Patients receive antitransferrin antibody A27.15 IV over 4 hours.” NCT00003082 ↗
Target TFRC “Transferrin receptor protein 1 antagonist” CHEMBL2109494 ↗