Drugs / Arbaclofen Placarbil
last change Jul 2017 re-read 2 minutes ago

Arbaclofen Placarbil

Small molecule

Developed for
gastroesophageal reflux disease · alcohol-related disorders · multiple sclerosis
Investigated by
XenoPort, Inc. · Indivior Inc.

Trials 6 · a red edge is where a trial was stopped

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02511886 Sep 2015 → Jan 2016 alcohol-related disorders Indivior Inc. Completed No outcome recorded
Phase 2 NCT00978016 Sep 2009 → Dec 2010 gastroesophageal reflux disease XenoPort, Inc. Completed No outcome recorded
Phase 2 NCT00817986 Dec 2008 → Jul 2009 XenoPort, Inc. Completed No outcome recorded
Phase 2 NCT00557973 Dec 2007 → Apr 2009 XenoPort, Inc. Completed No outcome recorded
Phase 2 NCT00557401 Nov 2007 → Sep 2008 gastroesophageal reflux disease XenoPort, Inc. Completed No outcome recorded
Phase 2 NCT00838396 Oct 2005 → Aug 2006 gastroesophageal reflux disease Indivior Inc. Completed No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03058237 Comparator Jan → Jul 2017 Indivior Inc. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT01359566 Comparator May 2011 → Feb 2013 multiple sclerosis XenoPort, Inc. Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as arbaclofen placarbil “The purpose of the study is to evaluate the efficacy and safety of arbaclofen placarbil (XP19986) compared to placebo in patients with gastroesophageal reflux disease.” NCT00838396
5

NCT00978016

NCT01359566

NCT03058237

NCT00817986

NCT02511886

Known as Arbaclofene placarbil ChEMBL registry synonym — accepted as the source's own label CHEMBL2107312
Known as Arbaclofeno placarbilo ChEMBL registry synonym — accepted as the source's own label CHEMBL2107312
Known as XP19986 “The purpose of the study is to evaluate the efficacy and safety of arbaclofen placarbil (XP19986) compared to placebo in patients with gastroesophageal reflux disease.” NCT00838396
2

NCT00557401

NCT00557973

Known as XP19986 SR1 “This is a multiple-dose, randomized, placebo-controlled crossover study of the efficacy and safety of XP19986 SR1 in subjects with spasticity due to spinal cord injury.” NCT00557973
Known as XP19986 SR3 XP19986 SR3, 20 mg QD” NCT00557401
Modality Small molecule CHEMBL2107312
Route Oral “XP19986 Sustained Release (SR) 20 mg tablet taken orally” NCT00557401