drugset
Drugs / CTS-1027
last change Dec 2011 re-read 3 minutes ago

CTS-1027

also known as RO-1130830 · RS-130830

Small molecule targets MMP12, MMP13, MMP14, MMP2, MMP3, MMP8, MMP9 via inhibition

Developed for
hepatitis C virus infection · chronic hepatitis C virus infection
Investigated by
Conatus Pharmaceuticals Inc. · FGK Clinical Research GmbH

Trials 4

today NCT01273064 · Ph 2 NCT01051921 · Ph 2 NCT00925990 · Ph 2 NCT00570336 · Ph 2
20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01273064 Jan → Sep 2011 hepatitis C virus infection Conatus Pharmaceuticals Inc. Terminated No outcome recorded
Phase 2 NCT01051921 Jan 2010 → Nov 2011 hepatitis C virus infection Conatus Pharmaceuticals Inc. Completed No outcome recorded
Phase 2 NCT00925990 Jun 2009 → May 2010 hepatitis C virus infection Conatus Pharmaceuticals Inc. Completed No outcome recorded
Phase 2 NCT00570336 Dec 2007 → Jul 2009 chronic hepatitis C virus infection Conatus Pharmaceuticals Inc. Completed No outcome recorded

Evidence & citations 13 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as CTS-1027 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01051921 ↗
3

NCT00925990 ↗

NCT01273064 ↗

NCT00570336 ↗
Known as RO-1130830 ChEMBL registry synonym — accepted as the source's own label CHEMBL440498 ↗
Known as RS-130830 ChEMBL registry synonym — accepted as the source's own label CHEMBL440498 ↗
Action Inhibit “Matrix metalloproteinase 13 inhibitor” CHEMBL440498 ↗
6

“Matrix metalloproteinase 14 inhibitor” CHEMBL440498 ↗

“Matrix metalloproteinase 12 inhibitor” CHEMBL440498 ↗

“Matrix metalloproteinase 8 inhibitor” CHEMBL440498 ↗

“Matrix metalloproteinase 3 inhibitor” CHEMBL440498 ↗

“Matrix metalloproteinase 9 inhibitor” CHEMBL440498 ↗

“Matrix metalloproteinase-2 inhibitor” CHEMBL440498 ↗
Modality Small molecule — CHEMBL440498 ↗
Route Oral “administered orally once daily” NCT00570336 ↗
Target MMP12 “Matrix metalloproteinase 12 inhibitor” CHEMBL440498 ↗
Target MMP13 “Matrix metalloproteinase 13 inhibitor” CHEMBL440498 ↗
Target MMP14 “Matrix metalloproteinase 14 inhibitor” CHEMBL440498 ↗
Target MMP2 “Matrix metalloproteinase-2 inhibitor” CHEMBL440498 ↗
Target MMP3 “Matrix metalloproteinase 3 inhibitor” CHEMBL440498 ↗
Target MMP8 “Matrix metalloproteinase 8 inhibitor” CHEMBL440498 ↗
Target MMP9 “Matrix metalloproteinase 9 inhibitor” CHEMBL440498 ↗