Drugs / adagloxad simolenin
adagloxad simolenin
Trials 3 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT03608878 | Apr → Dec 2019 | hepatocellular carcinoma | Chang Gung Memorial Hospital | Terminated | No outcome recorded |
| Phase 2 | NCT01516307 | Dec 2011 → Aug 2016 | breast cancer | OBI Pharma, Inc | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT03562637 | Dec 2018 → Dec 2025 overdue | triple-negative breast carcinoma | OBI Pharma, Inc | Active not recruiting | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | adagloxad simolenin | “PURPOSE: This randomized, double-blind, placebo-controlled, parallel-group, phase II trial assessed the efficacy and safety of adagloxad simolenin (OBI-822; a Globo H epitope...” PMID 32718986 ↗ Jul 2020 |
| Known as | AdaSim | “In a phase II study, adagloxad simolenin (AdaSim), a synthetic Globo H conjugate vaccine administered with adjuvant OBI-821, was shown to induce IgM and IgG anti-Globo H...” PMID 36268941 ↗ Oct 2022 |
| Known as | Globo H-KLH | “to form Adagloxad simolenin (OBI-822) (Globo H-KLH)” NCT03608878 ↗ |
| Known as | OBI-822 | “PURPOSE: This randomized, double-blind, placebo-controlled, parallel-group, phase II trial assessed the efficacy and safety of adagloxad simolenin (OBI-822; a Globo H epitope...” PMID 32718986 ↗ Jul 20202“The GLORIA Study: A Phase 3, Randomized, Open-Label Study of the Anti-Globo H Vaccine Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With High...” NCT03562637 ↗ “Adagloxad simolenin (OBI-822) is a glyco-conjugated protein comprised of a carbohydrate tumor antigen.” NCT03608878 ↗ |
| Known as | OPT-822 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3707279 ↗ |
| Modality | Vaccine | “Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821” PMID 32718986 ↗ Jul 2020 |