Drugs / ABN401
last change Dec 2025 re-read 3 minutes ago

ABN401

targets MET via inhibition

Developed for
cancer · neoplasm
Investigated by
Abion Inc · Novotech (Australia) Pty Limited · Yonsei University

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05248074 Jan → Feb 2022 cancer Abion Inc Completed No outcome recorded
Phase 1 NCT04052971 Aug 2019 → Nov 2023 cancer Abion Inc Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05882292 Nov 2023 → Dec 2025 overdue neoplasm Yonsei University Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as ABN401 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05248074 ↗
2

NCT05882292 ↗

NCT04052971 ↗

Action Inhibit “ABN401 competitively attaches to the ATP binding sites in the kinase domain of c-MET with high specificity to inhibit phosphorylation of downstream signaling pathways.” NCT05882292 ↗
Route Oral “Route of Administration: Oral” NCT04052971 ↗
Target MET “ABN401 competitively attaches to the ATP binding sites in the kinase domain of c-MET with high specificity to inhibit phosphorylation of downstream signaling pathways.” NCT05882292 ↗