Drugs / Ad5-yCD/mutTKSR39rep-hIL12
last change Jan 2024 re-read 3 minutes ago

Ad5-yCD/mutTKSR39rep-hIL12

also known as Ad5-IL-12
Developed for
prostate cancer
Investigated by
Henry Ford Health System

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02555397 Aug 2015 → Jun 2019 prostate cancer Henry Ford Health System Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Ad5-yCD/mutTKSR39rep-hIL-12 “In a phase I dose escalation and safety study (NCT02555397), a replication-competent oncolytic adenovirus expressing yCD, TK and hIL-12 (Ad5-yCD/mutTKSR39rep-hIL-12) was...” PMID 37713401 ↗ Sep 2023
1

NCT02555397 ↗

Known as Ad5-IL-12 “This trial confirmed that replication-competent Ad5-IL-12 adenovirus (Ad5-yCD/mutTKSR39rep-hIL-12) was well tolerated when administered locally to prostate tumors.” PMID 37713401 ↗ Sep 2023
Route Other “Single intraprostatic injection of Ad5-yCD/mutTKSR39rep-hIL12 on day 1” NCT02555397 ↗