Drugs / GRN1005
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT01679743 | Aug 2012 → Aug 2014 | breast cancer, lung cancer | National Cancer Institute (NCI) | Withdrawn | No outcome recorded |
| Phase 2 | NCT01497665 | Nov 2011 → Jan 2013 | non-small cell lung carcinoma | Angiochem Inc | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT01480583 | Oct 2011 → Jun 2015 | breast cancer, metastatic malignant neoplasm in the brain | Angiochem Inc | Completed | No outcome recorded |
Press releases naming this drug 7 releases
| Date | Issuer | Release |
|---|---|---|
| 2012-12-03 | Geron Corporation | Geron Discontinues GRN1005 and Restructures to Focus on Imetelstat Development in Hematologic Malignancies and Solid Tumors with Short Telomeres geron.com ↗ |
| 2011-12-27 | Angiochem Inc | GERON INITIATES PHASE 2 TRIAL OF GRN1005 IN BRAIN METASTASES FROM LUNG CANCER angiochem.com ↗ |
| 2011-12-22 | Geron Corporation | Geron Initiates Phase 2 Trial of GRN1005 in Brain Metastases From Lung Cancer geron.com ↗ |
| 2011-12-16 | Angiochem Inc | GERON INITIATES PHASE 2 TRIAL OF GRN1005 IN BRAIN METASTASES FROM BREAST CANCER angiochem.com ↗ |
| 2011-12-12 | Geron Corporation | Geron Initiates Phase 2 Trial of GRN1005 in Brain Metastases From Breast Cancer geron.com ↗ |
| 2011-11-15 | Angiochem Inc | GERON PRESENTS FINAL PHASE 1 CLINICAL DATA ON GRN1005 AT AACR-NCI-EORTC angiochem.com ↗ |
| 2011-11-15 | Geron Corporation | Geron Presents Final Phase 1 Clinical Data on GRN1005 at AACR-NCI-EORTC geron.com ↗ |
Evidence & citations 2 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | GRN1005 | “GRN1005 will be administered at a dose of 550 mg/m2 as an IV infusion at a rate of 8.0 - 8.5 mL/minute on Day 1 of 21-day cycle ( 3 days) and a second dose will be given on the...” NCT01679743 ↗ |
| Route | Intravenous | “550 mg/m2 IV every 3 weeks” NCT01480583 ↗ |