Drugs / Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes
last change Aug 2026 re-read 3 minutes ago

Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes

Cell therapy

Developed for
CD4+/CD56+ hematodermic neoplasm · acute myeloid leukemia
Investigated by
City of Hope Medical Center · Mustang Bio · National Cancer Institute (NCI)

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02159495 Dec 2015 → Aug 2026 overdue CD4+/CD56+ hematodermic neoplasm, acute biphenotypic leukemia, adult acute lymphoblastic leukemia City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Autologous CD123CAR-CD28-CD3zeta-EGFRt-expressing T Lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT02159495 ↗
Action Deplete “recognize and kill cancer cells” NCT02159495 ↗
Modality Cell therapy “genetically modified T-cells” NCT02159495 ↗
Route Intravenous “Given IV” NCT02159495 ↗