Drugs / HYODEOXYCHOLIC_ACID
last change Jun 2015 re-read 3 minutes ago

HYODEOXYCHOLIC_ACID

Small molecule targets NR1H2, NR1H3 via activation

Developed for
hyperlipidemia
Investigated by
AtheroNova Inc.

Trials 1

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01931241 Jun 2013 → Jun 2015 hyperlipidemia AtheroNova Inc. Unknown No outcome recorded

Evidence & citations 11 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as HYODEOXYCHOLIC_ACID ChEMBL registry synonym — accepted as the source's own label CHEMBL272621 ↗
Known as .alpha.-hyodeoxycholic acid ChEMBL registry synonym — accepted as the source's own label CHEMBL272621 ↗
Known as AHRO-001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01931241 ↗
Known as Hdca ChEMBL registry synonym — accepted as the source's own label CHEMBL272621 ↗
Known as Hyodesoxycholic acid ChEMBL registry synonym — accepted as the source's own label CHEMBL272621 ↗
Known as NSC-60672 ChEMBL registry synonym — accepted as the source's own label CHEMBL272621 ↗
Action Activate “LXR-alpha agonist” CHEMBL272621 ↗
1

“LXR-beta agonist” CHEMBL272621 ↗

Modality Small molecule — CHEMBL272621 ↗
Route Oral “Oral AHRO-001” NCT01931241 ↗
Target NR1H2 “LXR-beta agonist” CHEMBL272621 ↗
Target NR1H3 “LXR-alpha agonist” CHEMBL272621 ↗