Drugs / 90Y-ibritumomab tiuxetan

Trials 13

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/23 trials
Phase 1/2 NCT00761384 Apr 2008 → Jan 2016 B-cell neoplasm Lund University Hospital Completed No outcome recorded
Phase 1/2 NCT00397800 Jun 2005 → May 2008 lymphoma Technical University of Munich Unknown No outcome recorded
Phase 1/2 NCT00012298 Apr 2001 → Apr 2010 MALT lymphoma, Waldenstrom macroglobulinemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, nodal marginal zone B-cell lymphoma +1 National Cancer Institute (NCI) Terminated No outcome recorded
Phase 29 trials
Phase 2 NCT01490723 Jan 2013 → Apr 2019 leukemia, lymphoma M.D. Anderson Cancer Center Completed No outcome recorded
Phase 2 NCT01434472 Nov 2011 → May 2020 Burkitt lymphoma, diffuse large B-cell lymphoma, post-transplant lymphoproliferative disease Fred Hutchinson Cancer Center Terminated No outcome recorded Stop: Business
Phase 2 NCT00695409 Mar 2008 → Mar 2017 lymphoma City of Hope Medical Center Completed No outcome recorded
Phase 2 NCT00902525 Jan 2008 → Jan 2009 diffuse large B-cell lymphoma Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT01493479 Jun 2007 → Jan 2011 follicular lymphoma The Christie NHS Foundation Trust Completed No outcome recorded
Phase 2 NCT00310128 Feb 2006 → ? HIV-associated cancer, anaplastic large cell lymphoma AIDS Malignancy Consortium Withdrawn No outcome recorded
Phase 2 NCT00336843 Nov 2005 → Feb 2009 non-Hodgkin lymphoma Asan Medical Center Completed No outcome recorded
Phase 2 NCT00514475 Nov 2005 → Jun 2009 mantle cell lymphoma Oslo University Hospital Completed No outcome recorded
Phase 2 NCT00414089 — lymphoma AHS Cancer Control Alberta Withdrawn No outcome recorded Stop: Business
Phase 31 trial
Phase 3 NCT02320292 Feb 2015 → Feb 2021 B-cell non-Hodgkin lymphoma Mayo Clinic Terminated No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as 90Y-ibritumomab tiuxetan “90Y-ibritumomab tiuxetan is designed to attach to lymphoma cells and destroy the cells using a radioactive particle that is attached to it.” NCT01490723 ↗
6

“Combining 90Y-ibritumomab Tiuxetan With High-dose Chemotherapy” NCT00336843 ↗

“90Y-Ibritumomab tiuxetan, 0.4 mCi/kg, I.V.” NCT00336843 ↗

NCT01493479 ↗

NCT00514475 ↗

NCT00414089 ↗

NCT00902525 ↗

Known as (90)Y-IT “PURPOSE: We report an international, multicenter phase II trial to evaluate the efficacy and toxicity of fractionated (90)Y-ibritumomab tiuxetan ((90)Y-IT) as initial therapy...” PMID 24297953 ↗ Dec 2013
Known as 90Y-ibritumomab ClinicalTrials.gov intervention name — accepted as the source's own label NCT00761384 ↗
Known as Yttrium Y-90 Ibritumomab Tiuxetan “Radiolabeled monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan, can find cancer cells and carry cancer-killing substances to them without harming normal cells.” NCT00397800 ↗
5

“Patients receive yttrium Y 90 ibritumomab tiuxetan intravenously (IV) following rituximab IV on day -14.” NCT00695409 ↗

“Yttrium Y-90 Ibritumomab Tiuxetan” NCT01434472 ↗

“Yttrium Y-90 Ibritumomab Tiuxetan” NCT02320292 ↗

NCT00310128 ↗

NCT00012298 ↗

Known as yttrium-90-ibritumomab tiuxetan “Two Repeated Doses of Yttrium-90 Ibritumomab Tiuxetan (Zevalin®) as Salvage Treatment for Patients With Relapsed or Refractory Aggressive B-cell Lymphoma: a Phase II Study.” NCT00902525 ↗
1

“Yttrium-90-ibritumomab tiuxetan in combination with intravenous busulfan, cyclophosphamide, and etoposide followed by autologous stem cell transplantation” PMID 19547918 ↗ Jun 2009

Known as Zevalin “90Y-ibritumomab tiuxetan (Zevalin) at 0.4 mCi/kg is administered one week prior to start high-dose chemotherapy (BEAM/BEAC) in patients who have not achieved CR after induction therapy.” NCT00514475 ↗
2

“Two Repeated Doses of Yttrium-90 Ibritumomab Tiuxetan (Zevalin®) as Salvage Treatment for Patients With Relapsed or Refractory Aggressive B-cell Lymphoma: a Phase II Study.” NCT00902525 ↗

“90Y-ibritumomab tiuxetan (Zevalin)” NCT00414089 ↗

Action Inhibit “Monoclonal antibodies, such as rituximab and yttrium Y 90 ibritumomab tiuxetan, can block cancer growth in different ways.” NCT00310128 ↗
Modality Monoclonal antibody “Monoclonal antibodies, such as rituximab and yttrium Y 90 ibritumomab tiuxetan, can block cancer growth in different ways.” NCT00310128 ↗
Route Intravenous “yttrium Y 90 ibritumomab tiuxetan (IDEC-90Y2B8) IV over 10 minutes on day 8” NCT00012298 ↗