Drugs / tolododekin alfa
last change Dec 2025 re-read 2 minutes ago

tolododekin alfa

also known as ANK-101

Protein / enzyme biologic

Developed for
non-small cell lung carcinoma · skin squamous cell carcinoma · metastatic neoplasm · soft tissue neoplasm
Investigated by
Ankyra Therapeutics, Inc

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07100925 Dec 2025 → Jun 2030 skin squamous cell carcinoma Ankyra Therapeutics, Inc Withdrawn No outcome recorded
Phase 1 NCT07027514 Oct 2025 → Jun 2027 expected non-small cell lung carcinoma Ankyra Therapeutics, Inc Recruiting No outcome recorded
Phase 1 NCT06171750 Jan 2024 → Apr 2027 expected metastatic neoplasm, non-small cell lung carcinoma, skin squamous cell carcinoma, soft tissue neoplasm Ankyra Therapeutics, Inc Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as tolododekin alfa ClinicalTrials.gov intervention name — accepted as the source's own label NCT06171750
2

NCT07027514

NCT07100925

Known as ANK-101 “A study of tolododekin alfa (also known as ANK-101) administered prior to surgery in kidney transplant participants that also have high-risk cutaneous squamous cell carcinoma (CSCC).” NCT07100925
Modality Protein / enzyme biologic “Tolododekin alfa is a first-in-class anchored Interleukin 12 (IL-12) linked to aluminum hydroxide.” PMID 41022754 Sep 2025
Route Other “intratumoral (IT) injection” NCT06171750