Drugs / Flunisolide
Flunisolide
also known as
Aerobid · Aerospan · Aerospan hfa · Flunisolida · Flunisolide anhydrous · Flunisolide hemihydrate · Flunisolide-CFC · Flunisolide-HFA · +6 more
Small molecule targets NR3C1 via activation
Regulatory milestones approvals, filings & regulatory actions · 3 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | AEROSPAN HFA | — | 2013-08-28 | fda.gov ↗ |
| Label expansion | US (FDA) | NASALIDE | — | 1999-02-25 | fda.gov ↗ |
| Approved | US (FDA) | NASALIDE | — | 1981-09-24 | fda.gov ↗ |
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT00203684 | — | asthma, lung disorder | University of California, Los Angeles | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00346775 | May → Jun 2006 | perennial allergic rhinitis | GlaxoSmithKline | Completed | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| — | NCT02509299 Background | Sep → Nov 2019 | chronic obstructive pulmonary disease | University of Granada | Completed | No outcome recorded |
| — | NCT02515318 Comparator | Sep 2015 → Mar 2017 | chronic obstructive pulmonary disease | University of Granada | Unknown | No outcome recorded |
| — | NCT02404103 Comparator | Mar 2015 → May 2017 | childhood onset asthma | University of Louisville | Completed | No outcome recorded |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Flunisolide | “Inhaled glucocorticoids including beclomethasone dipropionate, budesonide, flunisolide, fluticasone propionate and triamcinolone acetonide, depending on the expert criteria.” NCT02509299 ↗4“Inhaled glucocorticoids including beclomethasone dipropionate, budesonide, flunisolide, fluticasone propionate and triamcinolone acetonide” NCT02515318 ↗ |
| Known as | Aerobid | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Aerospan | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Aerospan hfa | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Flunisolida | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Flunisolide anhydrous | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Flunisolide hemihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Flunisolide-CFC | “an inhaled corticosteroid that has a large particle size and should only reach the large airways (Flunisolide-CFC)” NCT00203684 ↗ |
| Known as | Flunisolide-HFA | “an inhaled, small particle corticosteroid that should reach both the large and small airways (Flunisolide-HFA)” NCT00203684 ↗ |
| Known as | Nasalide | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Nasarel | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | NSC-757871 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | RS-3999 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Syntaris | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Known as | Syntaris hayfever | ChEMBL registry synonym — accepted as the source's own label CHEMBL1512 ↗ |
| Action | Activate | “Glucocorticoid receptor agonist” CHEMBL1512 ↗ |
| Modality | Small molecule | — CHEMBL1512 ↗ |
| Route | Inhaled | “Patients will receive inhaled Flunisolide HFA 80 mcg twice per day” NCT02404103 ↗ |
| Target | NR3C1 | “Glucocorticoid receptor agonist” CHEMBL1512 ↗ |