Drugs / satavaptan
satavaptan
also known as
SR121463B · Aquilda · Satavaptan monophosphate · Satavaptan phosphate · SR 121463 · SR 121463A · SR121463F
Small molecule targets AVPR2 via inhibition
Trials 11
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 24 trials | ||||||
| Phase 2 | NCT00501384 | Apr 2004 → May 2005 | cirrhosis of liver | Sanofi | Completed | No outcome recorded |
| Phase 2 | NCT00501722 | Apr 2004 → Mar 2005 | cirrhosis of liver | Sanofi | Completed | No outcome recorded |
| Phase 2 | NCT00501566 | Apr 2004 → Jan 2005 | cirrhosis of liver | Sanofi | Completed | No outcome recorded |
| Phase 2 | NCT00032734 | Jun 2001 → Jul 2003 | inappropriate ADH syndrome | Sanofi | Completed | No outcome recorded |
| Phase 37 trials · 3 missed | ||||||
| Phase 3 | NCT00728091 | Jul → Dec 2008 | inappropriate ADH syndrome | Sanofi | Terminated | No outcome recorded |
| Phase 3 | NCT00366795 | Aug 2006 → Dec 2008 | cirrhosis of liver | Sanofi | Terminated | Missed primary |
| Phase 3 | NCT00359437 | Jul 2006 → Oct 2008 | cirrhosis of liver | Sanofi | Terminated | Missed primary |
| Phase 3 | NCT00358878 | Jul 2006 → Dec 2008 | cirrhosis of liver | Sanofi | Completed | Missed primary |
| Phase 3 | NCT00264914 | Jul 2005 → Aug 2007 | inappropriate ADH syndrome | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00274326 | May 2005 → Jul 2007 | congestive heart failure | Sanofi | Completed | No outcome recorded |
| Phase 3 | NCT00264927 | May 2004 → Sep 2007 | inappropriate ADH syndrome | Sanofi | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | satavaptan | “The aim of this study was to investigate the efficacy and safety of satavaptan, an oral AVP V(2)-receptor antagonist, in patients with dilutional hyponatraemia.” PMID 21199833 ↗ Jan 2011 |
| Known as | Aquilda | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Known as | Satavaptan monophosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Known as | Satavaptan phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Known as | SR 121463 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Known as | SR 121463A | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Known as | SR121463B | “satavaptan (SR121463B)” NCT00032734 ↗ |
| Known as | SR121463F | ChEMBL registry synonym — accepted as the source's own label CHEMBL2107777 ↗ |
| Action | Inhibit | “Vasopressin V2 receptor antagonist” CHEMBL2107777 ↗1“vasopressin receptor antagonist” NCT00032734 ↗ |
| Modality | Small molecule | — CHEMBL2107777 ↗ |
| Route | Oral | “subjects receive either capsules of SR121463B or a matching placebo” NCT00032734 ↗ |
| Target | AVPR2 | “Vasopressin V2 receptor antagonist” CHEMBL2107777 ↗ |