Drugs / LY2886721
last change Aug 2013 re-read 3 minutes ago

LY2886721

Small molecule

Developed for
Alzheimer disease
Investigated by
Eli Lilly and Company

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT01807026 Mar → May 2013 Alzheimer disease Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01775904 Feb → May 2013 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01534273 Feb → Jul 2012 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01367262 Jun → Jul 2011 — Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01227252 Dec 2010 → Apr 2011 Alzheimer disease Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01133405 Jun → Oct 2010 Alzheimer disease Eli Lilly and Company Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01561430 Mar 2012 → Aug 2013 Alzheimer disease Eli Lilly and Company Terminated No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2013-06-13 Eli Lilly and Company Results Lilly Voluntarily Terminates Phase II Study for LY2886721, a Beta Secretase Inhibitor, Being Investigated as a Treatment for Alzheimer's Disease lilly.com ↗
Eli Lilly and Company (NYSE: LLY) today announced it has stopped its Phase II study (BACC) for LY2886721, a beta secretase (BACE) inhibitor being investigated as a once daily treatment for its potential to slow the progression of Alzheimer's disease.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as LY2886721 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01534273 ↗
6

NCT01227252 ↗

NCT01133405 ↗

NCT01367262 ↗

NCT01775904 ↗

NCT01807026 ↗

NCT01561430 ↗

Modality Small molecule — CHEMBL2396989 ↗
Route Oral “Single (7 milligram (mg), 15 mg, 25 mg, 35 mg) doses of LY2886721 administered orally in up to three of three study periods” NCT01133405 ↗