Drugs / CLOTHIAPINE
last change Nov 2015 re-read 2 minutes ago

CLOTHIAPINE

also known as Clotiapine · Clotiapina · Entumin · HF-2159

Small molecule targets DRD4 via inhibition

Developed for
psychotic disorder
Investigated by
Fundación Pública Andaluza Progreso y Salud · Instituto de Salud Carlos III

Trials 1 · a red edge is where a trial was stopped

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01765829 Nov 2012 → Nov 2015 psychotic disorder Fundación Pública Andaluza Progreso y Salud Unknown No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01323205 Background May 2011 → Nov 2012 schizophrenia Janssen Research & Development, LLC Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CLOTHIAPINE ChEMBL registry synonym — accepted as the source's own label CHEMBL304902
Known as Clotiapina ChEMBL registry synonym — accepted as the source's own label CHEMBL304902
Known as Clotiapine “Regular antipsychotic medications (Risperidone, Olanzapine, Clozapine, Amisulpride, Quetiapine, Paliperidone, Aripiprazole, Haloperidol, Levomepromazine, Zuclopenthixol...” NCT01323205
1

“Drugs: Aripiprazole, Olanzapine, Zuclopenthixol, Clotiapine, Flupentixol, Risperidone, Sulpiride, Trifluoperazine, Haloperidol, Quetiapine, Paliperidone, Chlorpromazine,...” NCT01765829

Known as Entumin ChEMBL registry synonym — accepted as the source's own label CHEMBL304902
Known as HF-2159 ChEMBL registry synonym — accepted as the source's own label CHEMBL304902
Action Inhibit “Dopamine D4 receptor antagonist” CHEMBL304902
Modality Small molecule CHEMBL304902
Target DRD4 “Dopamine D4 receptor antagonist” CHEMBL304902