Drugs / DF6215
last change Dec 2025 re-read 3 minutes ago

DF6215

Protein / enzyme biologic

Developed for
cancer
Investigated by
Dragonfly Therapeutics · Merck Sharp & Dohme LLC

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06108479 Nov 2023 → Dec 2025 cancer Dragonfly Therapeutics Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2024-11-07 Dragonfly Therapeutics Results Dragonfly to Present Preclinical Data on Clinical-Stage DF6215, its Engineered IL-2R alpha-active Agonist, and DF9001, its EGFR-targeting TriNKET®, at SITC dragonflytx.com ↗
Data show that Dragonfly's DF6215 IL-2 cytokine drives greater therapeutic benefit in vivo than non-alpha IL-2, with no evidence of capillary leak syndrome or cytokine release syndrome .

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as DF6215 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06108479 ↗
Modality Protein / enzyme biologic “Immunotherapy (cytokine) targeting effector cells.” NCT06108479 ↗