Drugs / GLPG1205
last change Mar 2023 re-read 2 minutes ago

GLPG1205

Small molecule targets GPR84

Developed for
idiopathic pulmonary fibrosis · ulcerative colitis
Investigated by
Lakefront Biotherapeutics NV

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT04704739 Jan → Mar 2021 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT04532567 Aug → Dec 2020 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT03102567 Oct 2016 → Feb 2017 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT02623296 Oct 2015 → Feb 2016 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT02143856 May → Jul 2014 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT01887106 Jun → Sep 2013 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 22 trials
Phase 2 NCT03725852 Sep 2018 → Jul 2020 idiopathic pulmonary fibrosis Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 2 NCT02337608 Dec 2014 → Sep 2015 ulcerative colitis Lakefront Biotherapeutics NV Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as GLPG1205 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04704739
7

NCT02143856

NCT03102567

NCT04532567

NCT03725852

NCT02337608

NCT02623296

NCT01887106

Action Inhibit “GLPG1205 is a selective functional antagonist of G-protein-coupled receptor 84” PMID 36328358 Mar 2023
Modality Small molecule CHEMBL3716365
Route Oral “single ascending oral doses of GLPG1205” NCT01887106
Target GPR84 “Effect of GLPG1205, a GPR84 Modulator, on CYP2C9, CYP2C19, and CYP1A2 Enzymes” PMID 33955686 May 2021