Drugs / cinpanemab
last change Aug 2022 re-read 3 minutes ago

cinpanemab

also known as BIIB054 · Ni-202

Monoclonal antibody targets SNCA via inhibition

Developed for
Parkinson disease
Investigated by
Biogen

Trials 3

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03716570 Mar 2019 → Apr 2021 Parkinson disease Biogen Terminated No outcome recorded
Phase 1 NCT02459886 Jul 2015 → Nov 2017 Parkinson disease Biogen Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT03318523 Jan 2018 → Oct 2020 Parkinson disease Biogen Terminated Missed primary

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as cinpanemab “Cinpanemab, a human-derived monoclonal antibody that binds to α-synuclein, is being evaluated as a disease-modifying treatment for Parkinson's disease.” PMID 35921450 ↗ Aug 2022
Known as BIIB054 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03716570 ↗
1

NCT02459886 ↗

Known as Ni-202 ChEMBL registry synonym — accepted as the source's own label CHEMBL3833330 ↗
Action Inhibit “Alpha-synuclein inhibitor” CHEMBL3833330 ↗
Modality Monoclonal antibody “Cinpanemab, a human-derived monoclonal antibody” PMID 35921450 ↗ Aug 2022
1

CHEMBL3833330 ↗

Route Intravenous “IV infusion” NCT02459886 ↗
Target SNCA “Alpha-synuclein inhibitor” CHEMBL3833330 ↗