Drugs / RLY-2608

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05216432 Dec 2021 → Apr 2027 expected Her2-receptor negative breast cancer, PIK3CA-related overgrowth spectrum Relay Therapeutics, Inc. Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT06789913 Jun 2025 → Jul 2031 expected CLOVES syndrome, angioosteohypertrophic syndrome, lymphatic malformation, megalencephaly-capillary malformation-polymicrogyria syndrome +1 Relay Therapeutics, Inc. Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06982521 Aug 2025 → Apr 2028 expected hormone receptor-positive breast cancer Relay Therapeutics, Inc. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as RLY-2608 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06789913
2

NCT05216432

NCT06982521

Known as zovegalisib “This is a 3-part Phase 2 randomized study evaluating the safety and efficacy of the mutant-selective PI3Kα inhibitor, zovegalisib (RLY-2608), in adults and children with PIK3CA...” NCT06789913
Action Inhibit “PI3Kα inhibitor” NCT05216432
Modality Small molecule CHEMBL6068523
Route Oral “Multiple doses of RLY-2608 for oral administration.” NCT05216432